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f benzodiazepine hypnotics. Rebound insomnia, memory impairment, dependence and withdrawal are uncommon. Usual dose : 5-10mg, onset : 30 minutes, duration : 3-5 hours.
(B) Zaleplon
Although zaleplon has a pharmacologic profile similar to that of zolpidem, zaleplon offers a rapid absorption and onset of effect, no active metabolites, and an elimination half-life of one hour.
Duration : 2 hours. usual dose : 5-10mg. Zaleplon will be most useful for patients with sleep-onset insomnia but not those with early morning awakening.
Zaleplon is also useful for patients who need to take a hypnotic agent for rapid effect but who have limited time before they must awaken.
The most frequent adverse effects associated with zaleplon included dizziness and headache.
Zaleplon's very rapid onset and short duration of effect allows it the unique indication to be given anytime during the night as long as at least four hours of sleep time remain after dosing. Hypnotic drugs could not be given during the night or repeated during the night for fear of residual hang-over effects.

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